A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

Canadian company reports promising early Phase 1 test results of possible COVID-19 vaccine

Quebec City-based company says the side-effects were generally mild to moderate and short in duration

A Canadian biopharmaceutical company says it has received promising early test results for its plant-derived vaccine for COVID-19.

Privately held Medicago says interim results of a Phase 1 clinical trial found that 100 per cent of subjects developed an antibody response after two doses of its COVID-19 vaccine candidate.

“These are very promising results,” said Nathalie Landry, Medicago’s executive vice-president of scientific and medical affairs in a news release.

“We also observed that the antibody levels were higher after vaccination than those observed in convalescent sera from people who recovered from the disease.”

The Quebec City-based company says the side-effects were generally mild to moderate and short in duration.

The Phase 1 clinical trial was a randomized, partially blinded study of 180 healthy people.

Based on the Phase 1 data, Medicago plans to proceed with a Phase 2/3 clinical trial for its COVID-19 vaccine candidate, subject to regulatory approval.

The news comes a day after stock markets worldwide rallied on a report from Pfizer that a potential COVID-19 vaccine it’s developing with German partner BioNTech may be 90 per cent effective, based on early but incomplete test results.

“The positive results of our Phase 1 clinical trial are a step forward in the fight against the COVID-19 pandemic and we are confidently moving forward to our Phase 2/3 trial. We’re pleased that Medicago’s innovative manufacturing technology is helping to diversify the classes of COVID-19 vaccines candidates in development,” said CEO Dr. Bruce Clark.

The federal government has signed a deal with Medicago to secure the rights to buy 76 million doses of its vaccine.

VIDEO: Trudeau says he hopes to see COVID-19 vaccines roll out in Canada in early 2021

Medicago will also receive $173 million in funding from Ottawa for its vaccine research and development and for the construction of its Quebec City manufacturing facility.

Ottawa is also investing $18.2 million in a potential vaccine from British Columbia’s Precision NanoSystems and the National Research Council is to spend $23 million to support other Canadian vaccine initiatives.

Medicago was founded in 1999 and says its team includes over 450 scientific experts and employees in Canada and the United States, with academic affiliations in Europe and South Africa.

The Canadian Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Just Posted

Victoria-Swan Lake MLA Rob Fleming moves to the role of transportation minister in the NDP’s new cabinet. (B.C. government file photo)
Vancouver Island MLAs claim key roles in new cabinet

Key ministries headed by veteran and rookie Island MLAs in Horgan’s new team

Ladysmith’s 1st Avenue will be lit up until January 15. (Cole Schisler photo)
Ladysmith’s 1st Avenue all aglow

Although the tradition Light Up this year was cancelled, folks can still enjoy the holiday lights

Christmas will look a bit different in Cumberland this year, not only because of COVID restrictions but due to changes from BC Hydro about hanging decorations on the poles. Record file photo
Snowflakes left out in the cold for Island town

Holiday season tradition a no-go for Cumberland’s power poles

Karl Ablack, chair of the Port Renfrew Recovery Task Force, says visitors should steer clear of the community after the second wave of COVID has begun to hit across the province. (Black Press Media file photo)
Port Renfrew, Pacheedaht First Nation asks visitors to steer clear of community again

Tight-knit community of 400 has yet to report single case of COVID

The old home at 785 Island Rd. is coming down as the developer was unable to find a feasible business case to save it. (Black Press Media File Photo)
With no takers to move old Oak Bay home, teardown begins

‘We tried a last hurrah,’ developer says

Penny Hart is emotional outside the Saanich Police Department as she pleads for helpt to find her son Sean Hart last seen Nov. 6 at a health institution in Saanich. (Devon Bidal/News Staff)
VIDEO: Mother of missing Saanich man begs public to help find her son

Sean Hart last seen leaving Saanich mental health facility Nov. 6

Police in Nanaimo are looking for a suspect who wore a black-and-white striped hoodie and rode a yellow mountain bike when he allegedly stole three children’s backpacks from a daycare facility. (Photo submitted)
VIDEO: Thief steals children’s backpacks from Nanaimo daycare

Suspect rode a yellow mountain bike and made off with backpacks hanging on fence

The Klahoose First Nation village on Cortes Island is under lockdown until further notice due to a positive COVID-19 test. Photo courtesy Kevin Peacey.
Cortes Island First Nation community locked down due to positive COVID-19 test

Klahoose First Nation has had one positive test, one other potential case

North Island-Powell River MP Rachel Blaney has spoken out about some veterans losing their Dimished Earning Capacity income. (Mike Davies/Campbell River Mirror photo)
Blaney pens letter to minister about veteran supports

Concerned about veterans losing some income

The baby boy born to Gillian and Dave McIntosh of Abbotsford was released from hospital on Wednesday (Nov. 25) while Gillian continues to fight for her life after being diagnosed with COVID-19.
B.C. mom with COVID-19 still fighting for life while newborn baby now at home

Son was delivered Nov. 10 while Gillian McIntosh was in an induced coma

No face-offs until at least Dec. 8 after the BCHL shuts down pre-sesason play. (Citizen file)
BCHL cancels remainder of the pre-season

Island teams see their exhibition season cut short

Arthur Topham has been sentenced to one month of house arrest and three years of probation after breaching the terms of his probation. Topham was convicted of promoting hate against Jewish people in 2015. (Photo submitted)
Quesnel man convicted for anti-Semitic website sentenced to house arrest for probation breach

Arthur Topham was convicted of breaching probation following his 2017 sentence for promoting hatred

Langley School District's board office. (Langley Advance Times files)
‘Sick Out’ aims to pressure B.C. schools over masks, class sizes

Parents from Langley and Surrey are worried about COVID safety in classrooms

B.C. Premier John Horgan, a Star Trek fan, can’t resist a Vulcan salute as he takes the oath of office for a second term in Victoria, Nov. 26, 2020. (B.C. government)
Horgan names 20-member cabinet with same pandemic team

New faces in education, finance, economic recovery

Most Read